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Search Results for " sh 5 "

12

Compounds

Cat No. Product Name Synonyms Targets
T34632 SH-5 SH5 PIA5. LchiroInositol 1deoxy6Omethyl 5(2R)2methoxy3(octadecyloxy)propyl hydrogen phosphate. Akt inhibitor II
SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IκBα kinase activation.
TQ0052 SH5-07 STAT
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
T15900 M-PEG5-SH Others
m-PEG5-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within ...
T1567 Olanzapine LY170053 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T16079 Mirodenafil SK3530 PDE
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T2264 AM281 Cannabinoid Receptor
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.
TQ0126 Mirodenafil dihydrochloride SK-3530 dihydrochloride PDE
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T2625 MK-0752 Beta Amyloid , Gamma-secretase
MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
T9169 MPP+ iodide Mitochondrial Metabolism , Autophagy
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...
T35689 MTP 131 acetate Others
MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...
T83875 HUP-55
HUP-55 is a prolyl endopeptidase inhibitor with an IC50 of 5 nM, shown to mitigate α-synuclein dimerization in Neuro2a cells, stimulate autophagy in HEK293 cells, and lower hydrogen peroxide-evoked reactive oxygen specie...
T37114 SB 242084 dihydrochloride
SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonistin vitro: SB 242...
TargetMol